Transplant immunology is a medical science ensuring optimal donor-recipient matching before allogeneic transplantation of cells, tissues and solid organs. Allogeneic transplantation is a complex process involving transplant immunology, donor availability, appropriate criteria, coordination, and specialized medical staff. Oslo University Hospital requires a laboratory information system for transplant immunology, integrated with decision support systems, workflow mapping and post-transplant control registries.

Our team combines the IT skills and HLA experience of Steiner, s.r.o. staff with the laboratory and clinical knowledge of the medical staff of the University Hospital in Oslo. Since all transplant immunology, organ transplantation and HLA matching for stem cell transplantation in Norway take place in one center, we have a unique opportunity to develop and test the benefits of the new Transplant Immunology Decision Support System (TRIMMUS). This includes all the steps from registering samples in the Transplant Immunology Laboratory through decision support tools to connecting available donors with recipients to evaluating long-term results after allogeneic transplantation. TRIMMUS replaces manual data transfer, reducing the risk of human error. TRIMMUS will also present all relevant data and run algorithms to facilitate fast and appropriate advice and decision-making, thereby providing the best possible care.

Steiner supplies the software technology, and the University Hospital of Oslo provides medical expertise to develop algorithms and evaluate the performance of each algorithm and the entire solution. The outputs of the post-transplant conclusions will be used to improve pre-transplant search algorithms.

Thanks

The Transplant Immunology Decision Support System (TRIMMUS) received €1.2 million in support from Iceland, Liechtenstein and Norway through EEA grants and the Technology Agency of the Czech Republic under the KAPPA programme.